Frequency of Viral Replication Markers in Chronic HBV Carriers in N’Djamena, Chad

Introduction: According to the WHO, Chad is located in an area of high endemicity for hepatitis B virus (HBV). The aim this study was analyze virological profiles chronic HBV carriers. Materials and Method: This a retrospective analytical including outpatients with any age received Department Internal Medicine Gastroenterology National General Reference Hospital N’Djamena from 2013 2017. Results: During period, 401 carriers (mean 35 years ± 11 sex ratio 3.26) were seen outpatient clinic frequency 3.34% (401/11,988). HBeAg (+) patients 12.8% negative 87.2%. HBeAg-negative significantly older (p = 0.000) than those (+). mean HBV-DNA level higher patients. HBeAg-positive significant difference 0.043). ALT 45 IU/L (−) It 49 Conclusion: most predominant form our study. observation important because it can help adapt management strategies.